منابع مشابه
Keratinization and its disorders.
Keratins are a diverse group of structural proteins that form the intermediate filament network responsible for maintaining the structural integrity of keratinocytes. In humans, there are around 30 keratin families divided into two groups, namely, acidic and basic keratins, which are arranged in pairs. They are expressed in a highly specific pattern related to the epithelial type and stage of c...
متن کاملKeratinization Disorders and Genetic Aspects in Palmar and Plantar Keratodermas.
Palmoplantar keratoderma (PPK) is a heterogeneous group of hereditary and acquired disorders characterized by abnormal thickening of the palms and soles. There are three clinical patterns: diffuse, focal, and punctuate. Palmoplantar keratodermas can be divided into the following functional subgroups: disturbed gene functions in structural proteins (keratins), cornified envelope (loricrin, trans...
متن کاملMyeloproliferative disorders and its associated mutations
Myeloproliferative Neoplasm (MPN) are a clonal disorder in hematopoietic stem cells (HSC). MPN is categorized to 8 subclasses, including chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocytopenia (ET), primary myelofibrosis (PMF), systematic mastositosis (SM), chronic eosinophilic leukemia (CEL), chronic neutrophilic leukemia (CNL), and unclassified myelofibrosis disorde...
متن کاملSulfur-containing Proteins and Epidermal Keratinization
Sites of synthesis of sulfur-containing protein in keratinizing epithelium have been studied by radioautography after injection of sulfur-labeled cystine. Bern et al. (3) demonstrated concentration of silver grains immediately below the cornified layer, suggesting that much of sulfur is added at the final stages of keratinization as observed in hair. In contrast, B6langer (4) reported that prot...
متن کاملINsOmNIa aND ITs DIsORDeRs
Each of us will spend about 27 years of his or her lifetime sleeping. This fact alone explains why neuro-anatomists and neuro-physiologists have been studying sleep for over a century. The epidemiology of sleep, however, is a relatively young field of study, although physicians have always been interested in knowing how widespread abnormal sleep phenomena are in the population. The field of sle...
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ژورنال
عنوان ژورنال: Oman Medical Journal
سال: 2012
ISSN: 1999-768X,2070-5204
DOI: 10.5001/omj.2012.90